Recombinant Human KGF-北京科瑞美科技有限公司

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名稱	Recombinant Human KGF
型號
更新時間	2022-09-24
特點	FGF-7是已知的FGF家族的成員。這個家庭中發揮核心作用的蛋白質在產前發展和產后的生長和再生各種組織,通過促進細胞增殖和分化。FGF-7是一個特定的上皮細胞和角化細胞分裂素因素。 FGF-7信號通過FGFR 2 b。FGF-7腎和肺發展中所起的作用,血管再生和傷口愈合。FGF-7 18.9 kDa蛋白由163個氨基酸殘基組成。使用所有無動物生產試劑。}

詳細內容

一.產品名稱：Recombinant Human KGF

二.Catalog Number:AF-100-19

三.Synonyms:Keratinocyte Growth Factor, Fibroblast Growth Factor-7, HBGF-7

四.Description:

KGF/FGF-7 is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. KGF/FGF-7 is a mitogen factor specific for epithelial cells and keratinocytes. KGF/FGF-7 signals through FGFR 2b. KGF/FGF-7 plays a role in kidney and lung development, angiogenesis, and wound healing. Recombinant human KGF/FGF-7 is a 18.9 kDa protein consisting of 163 amino acid residues. Manufactured using all non-animal reagents.

五.AA Sequence:

CNDMTPEQMA TNVNCSSPER HTRSYDYMEG GDIRVRRLFC RTQWYLRIDK RGKVKGTQEM KNNYNIMEIR TVAVGIVAIK GVESEFYLAM NKEGKLYAKK ECNEDCNFKE LILENHYNTY ASAKWTHNGG EMFVALNQKG IPVRGKKTKK EQKTAHFLPM AIT

六.Source:E.coli

七.Purity:Greater than 95% by SDS-PAGE gel and HPLC analyses.

八.Biological Activity:

The ED₅₀ as determined by the dose-dependent stimulation of thymidine uptake by KGF-responsive BaF3 cells is ≤ 10 ng/ml corresponding to a specific activity of ≥ 1 x 10⁵ units/mg.

九.Cross Reactivity:Human, Rat, Mouse